Please go through quickly the msds of n butyl lithium nbuli it is a pyrophoric compound normally available commercially as a solution in a hydrocarbon solvent lithium is a toxic element. Organometallics are useful reagents, catalysts, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, led manufacturing, and others. Hexane n hexane 20 72 as published by safe work australia. Skin contact wash off immediately with plenty of water for at least 15 minutes. Occupational polyneuropathy has resulted from hexane exposures as low as 500 ppm, but the minimum levels of n hexane that are neurotoxic in humans havent been established. Hexane 7 section 16 other information msds creation date. The reactions of nbutyllithium or tbutyllithium are generally carried out in simple hydrocarbons such as pentane and hexane, ethers such as diethyl ether or thf and tertiary amines such as. In iupac nomenclature, however, hexane is the unbranched isomer nhexane. Hexanes typically contain a high proportion of nhexane. However, reading these procedures does not substitute for handson training. Procedures for safe use of pyrophoric solids, 22009 page 1 of 4 procedures for safe use of pyrophoric solids researchers should not use pyrophoric reagents until they have read and fully understood these safe operating procedures. Sra class sop and to specific safety data sheets sds of chemicals in use see section. This reagent is generally a mixture of several isomers of hexane c6h14. Hexane is expected to rapidly volatilize leaving a deposit of nbutyllithium behind.
Prolonged or repeated skin contact may cause defatting and dermatitis. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Material safety data sheet section 1 chemical product and company identification msds name. Heating may cause a fire in contact with water releases flammable gases which may ignite spontaneously may cause fire or explosion. Procedures for safe use of pyrophoric solids, 22009 page 3 of 4 specific recommendations for working with pyrophoric solid reagents lithium aluminum hydride reacts violently with water and has a. Sensitivity to static discharge yes sensitivity to static impact not applicable 5. Fisher scientific 1 reagent lane fair lawn, nj 07410 for information, call. Hexanes are a clear, colorless, highly flammable liquid with a gasolinelike odor although odorless when pure. Afterwards, lithium chloride is removed and the solution is concentrated to as much as 90% ww. Ghs h statement h225h250h260h252h304h361h373h314h336 highly flammable liquid and vapor.
Each notification may be associated with multiple companies. First aid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Overexposure to hexane may cause progressive and potentially irreversible damage to the peripheral nervous system, particularly in the arms and legs. Safety data sheet northwest missouri state university. Your new online msds binder is a place for you to store. The starting material is fairly soluble in the solvent, but not at all in hexane, which is how the nbuli usually comes, i was wondering if. Organolithium formation is carried out in hydrocarbon solvents. Shop online for a wide selection of nbutyllithium, 2. March 23, 2015 page 1 of 20 quenching of pyrophoric materials quenching of pyrophoric materials h250 h251 h252 examples.
Your new online msds binder is a place for you to store the material safety data sheets you need to. Extreme high moderate low section 1 chemical product and company identification product name. Risa benwell spl program manager office 650 9266283. The term hexanes cas 110543 refers to a hydrocarbon distillation fraction that contains a mixture of linear and branched hexane isomers.
No smoking p233 keep container tightly closed p240 groundbond container and receiving equipment. Material safety data sheet hexane 7 section 16 other information msds creation date. Twa the timeweighted average airborne concentration over an eighthour working day, for a fiveday working week over an entire working life. Sigmaaldrich 401757 page 1 of 8 sigmaaldrich material safety data sheet version 4. H261 in contact with water releases flammable gases. Hexane is expected to rapidly volatilize leaving a deposit of n butyllithium behind.
In contact with water releases flammable gases which may ignite spontaneously danger substances and mixtures which in contact with water, emit. P202 do not handle until all safety precautions have been read and. The interdependent properties, such as pyrophoricity, solubility, stability, and aggregation, are tabulated and discussed. The interdependent properties, such as pyrophoricity, solubility. Identification of the substancemixture and of the companyundertaking 1. Also, it is broadly employed as a strong base in the synthesis of organic compounds as in the pharmaceutical industry. Preparation, properties, and safe handling of commercial.
Sodium initiates and accelerates this highly exothermic reaction. In case of contact, immediately flush eyes with flowing water for at least 15 minutes. Product and company identification product name n butyllithium, 2. Material safety data sheet northwest missouri state. Click to download the latest version of adobe reader. Safety data sheet according to 29cfr19101200 and ghs rev. No warranty, express or implied, is made and labchem inc. Similarly, flush doubletipped needles with hexane and then quench. It is widely used as a polymerization initiator in the production of elastomers such as polybutadiene or styrenebutadienestyrene. Show this safety data sheet to the doctor in attendance. Health 3 4 fire 3 3 2 reactivity 2 personal protection.
In contact with water releases flammable gases which may ignite spontaneously. Reproductive effects experiments have shown reproductive toxicity effects on laboratory animals. Hexane 110543 not listed not listed not listed not listed not listed mutagenic effects mutagenic effects have occurred in experimental animals. Insoluble in water, it is soluble in ether, alcohol, and acetone. It is widely used as a polymerization initiator in the production of elastomers such as polybutadiene or styrenebutadienestyrene sbs. Other companies are charging thousands of dollars to set up accounts and give you access to their. To use this application, you will need the latest version of adobe reader. Stel short term exposure limit the average airborne concentration over a 15 minute period which should not. Butyllithium 15% solution in n hexane for synthesis find msds or sds, a coa, data sheets and more information. These properties have a direct bearing on their chemical reactivity and requirements for safe handling and storage.
The term may refer to any of the five structural isomers with that formula, or to a mixture of them. Safety data sheet creation date 26oct2009 revision date 05jul2019 revision number 4 1. Grace tang ssrl user lab manager office 650 9263467. Material safety data sheet instant fame reagent 2 hexane microbial id chemicals msds hexane 2 chronic.
It is also broadly employed as a strong base superbase in organic synthesis, both industrially and in the laboratory. None information in this msds is from available published sources and is believed to be accurate. Butyllithium is widely use as a polymerization initiator in the production of elastomers such as polybutadiene or styrenebutadienestyrene sbs. The information presented herein is believed to be accurate and reliable, but is. Hazard statements h225 highly flammable liquid and vapour. Draw hexane into the syringe containing small amounts of pyrophoric reagent and then discharge the diluted solution into isopropanol. Extreme high moderate low section 1 chemical product and company identification. Hexane microbial id chemicals msds hexane 1 section 1 chemical product and company identification msds name. Hexanes, acs safety data sheet according to federal register vol. Hydrocarbons, c6, nalkanes, isoalkanes, cyclics, nhexane rich.
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